If you wish to continue using the CloudMade services after April 30th you'll need to upgrade to an enterprise plan. Enterprise plans are available for customers with 10,000,000 or more transactions per month....
If your monthly usage is less than 10,000,000 transactions, or you don't wish to upgrade to an enterprise plan, you should take action to update the app or website that's using the CloudMade API keys shown above to use an alternative provider.