It probably tries to open the b4a file with the wrong executable. Right click on the project file and choose Open with... Select B4A.exe and check the "always use this program".
Just installed V5.00 and found similar to above .. clicking on app desktop shortcut resulted in "B4A has Stopped working ... "
As Erel suggested above .. Right click on the project file and choose Open with... Select B4A.exe and check the "always use this program".
all desktop shorcuts (I have quite a few.. ) opened correctly from then on.